|
Uniform Policies
PREAMBLE:
The following Uniform Policies are designed primarily for the guidance of State Pesticide Control Officials in
those states which have adopted the Uniform State Pesticide Act, but should be used by
other state officials insofar as their statutes will permit.
REGISTRATION
Resolved that the uniform application forms for registration should be used by state control officials.
Two specimens or exact copies of the labeling of each proposed product should be submitted
with the application. Also, there should be submitted the name and percentage of each
active ingredient and the total percentage of inert ingredients in the product, the
proposed directions for use, and a list of the specific pests for control of which it is
to be sold, if such information is not contained in the labeling. Such other pertinent
information concerning inert ingredients and physical properties of the product shall also
be included on request. (Tentative 1967) (Adopted 1968)
Resolved that products which are discontinued by a manufacturer be reregistered for a period of two years.
Said two year limit covers the year in which the item is declared to be discontinued by the
registrant and one additional year to permit time for distributors to dispose of shelf
stocks. (Revised, Tentative 1970) (Adopted 1971)
REGULATIONS
Advance notices of proposed rules,
regulations, restricted lists, amendments, related subjects and hearings thereon should be
sent to all pesticide registrants of record, and to trade associations that have so
requested, in order to develop useful information from these interested parties. Since
many have no other source, notices should preferably be mailed as early as possible but
as least for delivery at the time of publication of the local notice of hearing.
NOTE: Deleted uniform policies were adopted many years ago
and have become obsolete through preemption by provisions in FIFRA or its regulations.
Allowed Deviations of Analytical Results from Label Claims
for Active Ingredients in Pesticide Formulations
(Adopted by AAPCO March, 1998)
The Laboratory Liaison Committee suggests that the allowed deviations of analytical results from label claims on
pesticide formulation be based on Horwitz’ expected Standard Deviation (HSD)
calculations (Horwitz, Analytical Chemistry 54:1, 67A-76A, 1982). The following
equations are used to calculate allowed deviations:
Horwitz Between-Laboratory Coefficient of Variation = HCV(%) = 2(1 - 0.5 log (claim%/100))
Horwitz Standard Deviation = HSD = (Claim%)(HCV%)/100
In general, a "passed" judgment on a pesticide formulation can be made if the analytical results
are within the following guidelines:
for "uniform" samples: -3HSD/+6HSD
for "non-uniform" samples: -4HSD/+8HSD
For examples of allowed deviations, please refer to the following table.
Additional considerations:
"Uniform" samples are homogeneous products which can be analyzed by established procedures. In most cases, validated
analytical methods are available for these samples.
Non-uniform" samples are non-homogeneous samples or products which are difficult to sample or subsample.
These products may not be uniformly mixed or packaged and include some special formulations like natural products.
These types of samples include fertilizer containing pesticides, pesticides in pressurized
containers, strips, plastic bands, collars, grain and other carriers. Natural product
formulations such as rotenone and pyrethrin are also included in this group. When it is
necessary to use methods which are not validated for accuracy, precision, and
reproducibility in a specific matrix, the "non-uniform" guidelines may be used
for allowed deviations. States may use judgment in placing a sample into the
"uniform" or "non-uniform" category.
Examples for Allowed Deviations of Analytical Results from Label Claims
for Active Ingredients in Pesticide Formulations
|
for Active Ingredients in Pesticide Formulations Claim
% |
HCV(1)
% |
HSD(2) |
Allowed Deviations
for "uniform" samples |
Allowed Deviations for
"non-uniform" samples |
|
Claim - 3HSD |
Claim + 6HSD |
Claim - 4HSD |
Claim + 8HSD |
|
0.001 |
11.31 |
0.00011 |
0.00066 |
0.00168 |
0.00055 |
0.00191 |
|
0.005 |
8.88 |
0.00044 |
0.0037 |
0.0077 |
0.0032 |
0.0086 |
|
0.008 |
8.27 |
0.00066 |
0.0060 |
0.0120 |
0.0054 |
0.0133 |
|
0.01 |
8.00 |
0.00080 |
0.0076 |
0.0148 |
0.0068 |
0.0164 |
|
0.03 |
6.78 |
0.0020 |
0.024 |
0.042 |
0.022 |
0.046 |
|
0.06 |
6.11 |
0.0037 |
0.049 |
0.082 |
0.045 |
0.089 |
|
0.10 |
5.66 |
0.0057 |
0.083 |
0.13 |
0.077 |
0.145 |
|
0.40 |
4.59 |
0.018 |
0.34 |
0.51 |
0.33 |
0.55 |
|
0.80 |
4.14 |
0.033 |
0.70 |
1.00 |
0.67 |
1.06 |
|
1.0 |
4.00 |
0.040 |
0.88 |
1.24 |
0.84 |
1.32 |
|
2.0 |
3.60 |
0.072 |
1.78 |
2.43 |
1.71 |
2.58 |
|
4.0 |
3.25 |
0.13 |
3.61 |
4.78 |
3.48 |
5.04 |
|
6.0 |
3.05 |
0.18 |
5.45 |
7.10 |
5.27 |
7.47 |
|
10.0 |
2.83 |
0.28 |
9.15 |
11.70 |
8.87 |
12.26 |
|
15.0 |
2.66 |
0.40 |
13.80 |
17.39 |
13.40 |
18.19 |
|
20.0 |
2.55 |
0.51 |
18.47 |
23.06 |
17.96 |
24.08 |
|
25.0 |
2.46 |
0.62 |
23.15 |
28.70 |
22.54 |
29.93 |
|
30.0 |
2.40 |
0.72 |
27.84 |
34.32 |
27.12 |
35.75 |
|
35.0 |
2.34 |
0.82 |
32.54 |
39.92 |
31.72 |
41.56 |
|
40.0 |
2.30 |
0.92 |
37.25 |
45.51 |
36.33 |
47.35 |
|
45.0 |
2.26 |
1.01 |
41.96 |
51.09 |
40.94 |
53.12 |
|
50.0 |
2.22 |
1.11 |
46.67 |
56.66 |
45.56 |
58.88 |
|
60.0 |
2.16 |
1.30 |
56.11 |
67.78 |
54.82 |
70.37 |
|
70.0 |
2.11 |
1.48 |
65.57 |
78.86 |
64.09 |
81.82 |
|
80.0 |
2.07 |
1.65 |
75.04 |
89.93 |
73.38 |
93.24 |
|
90.0 |
2.03 |
1.83 |
84.51 |
100.97 |
82.68 |
104.63 |
(1) HCV(%) = Horwitz Coefficients of Variation = 2 (1 - 0.5 log (clairn%/100))
(2) HSD = Horwitz Standard Deviation = (Claim %)(HCV %)/100
|
